Health Condition 1: L409- Psoriasis, unspecified
Conditions
Interventions
Intervention1: Synbiotic: Each hard gelatin capsule contains:
lactobacillus acidophilus-700 MILLION, lactobacillus rhamnosus -400 MILLION, lactobacillus Casei-300 MILLION, lactobacillus Plantarum -30
Sponsors
DrHarshitha Vani
Eligibility
Inclusion criteria
Inclusion criteria: -Patients aged 18 to 60 years either gender. -Clinically diagnosed with psoriasis and on stable treatment for the past 3 months. -Willingness to provide written informed consent.
Exclusion criteria
Exclusion criteria: -Patients requiring any change in the psoriasis medication during the study period. -Patients with other autoimmune or chronic inflammatory skin diseases -Patients on antibiotics, probiotics, prebiotics or synbiotic therapy within past 6 weeks . -Patients with history of gastrointestinal diseases ( Eg. IBD ,celiac disease) -Patients with severe comorbidity/ major systemic illness ( Eg. Uncontrolled diabetes, active malignancy) -History of immunosuppressive drug consumption except topical steroids -Pregnant and lactating women. -Known or suspected allergy or intolerance to probiotics, prebiotics, dairy proteins or supplement excipients. -Participation in another clinical trial within the past 30 days.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| -To assess the impact of synbiotic supplementation as an add on therapy, onthe quality of life on psoriasis patients using DLQI (Dermatology life quality index) -To assess the patient safety and acceptability of synbiotic supplementationTimepoint: over an 8 week period. | — |
Primary
| Measure | Time frame |
|---|---|
| -To evaluate the effect of synbiotic supplementation as an add on therapy, on the clinical severity of psoriasis using PASI ( Psoriasis area severity index) score over an 8 week period.Timepoint: over an 8 week period. | — |
Countries
India
Contacts
Public ContactDrHarshitha Vani
Sri Manakula Vinayagar Medical College And Hospital
Outcome results
None listed