A study comparing two treatments to reduce long-term knee pain in arthritis patients nerve blockade by ablation vs steroid injection using ultrasound guidance

Comparative study to assess the analgesic efficacy of Cooled Radio Frequency Ablation of genicular nerve and Intra Articular CorticoSteroids, under ultrasound guidance for chronic knee pain from Osteoarthritis knee. - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092943

Enrollment

Registered

2025-08-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: Radio frequency ablation: Cooled radio frequency ablation of genicular nerves to treat OA knee pain Control Intervention1: Intra articular steroids: Intra articular corticosteroids to t

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with ACOR criteria with radiological evidence but not willing for surgery

Exclusion criteria

Exclusion criteria: Patient refusal, bleeding diathesis, previous Intra articular injection in last 3 months, previous knee surgeries, rheumatoid arthritis, ligament injuries

Design outcomes

Primary

Measure	Time frame
To compare analgesic efficacy of cooled RFA of genicular nerve and Intra articular cortico steroids under ultrasound guidance for chronic knee pain in OA kneeTimepoint: Time point of pain assessment pre procedure, immediately after procedure, 24 hrs, 1 week, 2 week and 4 week interval	—

Secondary

Measure	Time frame
To assess improvement of knee functionTimepoint: Assessed using WOMAC score	—

Countries

India

Contacts

Public ContactV Vaishnavi

vaishu.8492@gmail.com9789993988

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026