Health Condition 1: J22- Unspecified acute lower respiratory infection
Conditions
Interventions
Intervention1: Titrated supplement of nutrition: addition of titrated Ryles tube feed based on diaphragm thickness and excursion monitered by Ultrasound in mechanically ventilated patients in ICU
Con
Sponsors
All Institute of Medical SciencesJodhpur
Eligibility
Inclusion criteria
Inclusion criteria: Mechanically ventilated patients in view of altered sensorium
Exclusion criteria
Exclusion criteria: Refusal of informed consent Known case of phrenic nerve injury Patients with chest trauma, abdominal trauma Patients with pathologies related to increased abdominal pressure Patients with neuromuscular muscular diseases Continuous infusion of muscle-paralyzing agents abnormal values of myocardial and muscular damage markers at ICU admission, presence of thoracotomy, pneumothorax or pneumo-mediastinum, pregnancyPatients with previous history of delirium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weaning of mechanically ventilated patients between titrated calorie administration during the initial 1 week and fixed calorie administration during the 1 st week in mechanically ventilated patients in ICUTimepoint: Weaning of mechanically ventilated patients between titrated calorie administration during the initial 1 week and fixed calorie administration during the 1st week in mechanically ventilated patients in Icu | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess diaphragm thickness at 1st week serum phosphate level at days 0,3 & 7th day IL-6 marker of oxidant injury on day 7 Difficulty in weaning from mechanical ventilator after 1 week of ventilation To assess the efficacy & outcome of patients who undergo graded increase in nutrition over 1 month To assess the efficacy & outcome of patients who undergo graded increase in nutrition To assess the Gastrointestinal issues Imbalance of hyperglycemia eventsTimepoint: To assess diaphragm thickness at 1st week serum phosphate level at days 0,3 & 7th day IL-6 marker of oxidant injury on day 7 Difficulty in weaning from mechanical ventilator after 1 week of ventilation To assess the efficacy & outcome of patients who undergo graded increase in nutrition over 1 month | — |
Countries
India
Contacts
Public ContactMukund Sajjan
All Institute of Medical Sciences,Jodhpur
Outcome results
None listed