Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas
Conditions
Interventions
Intervention1: ANTIBIOTIC DURATION: Patients undergoing pancreaticoduodenectomy, divided in two groups - Group A and B.Each patient will be assigned to one of two groups through the use of a set of se
Sponsors
POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients willing to give consent to participate in the study 2.Either gender 3. AGE 18-80years 4.Patient undergoing elective- Whipple - pancreaticoduodenectomy for benign and malignant etiology 5. Injection Piperacillin +tazobactam 4.5g IV four times a day will be given empirically. Antibiotic will be replaced according to intraoperative bile culture and sensitivity 6.Renal dose adjustment of antibiotic done in patients with renal impairment
Exclusion criteria
Exclusion criteria: 1.Patient not giving informed consent 2.Patients undergoing total pancreatectomy, distal pancreatectomy, enucleation 3.Postoperative complications other than infectious complications 4.If patients of group A develop prolonged septic complications requiring extended antibiotic course will either be excluded or be accounted in group B 5.Patient operated outside, lost to follow up, developing organ failure and requiring ICU admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TO ASSESS CORRELATION BETWEEN THE REDUCTION IN INCIDENCE OF SURGICAL SITE INFECTIONS AND ANTIBIOTIC DURATION IN PATIENTS UNDERGOING PANCREATICODUODENECTOMYTimepoint: Outcomes will be assessed postoperatively at the baseline during hospital stay, 1 month and 3 months after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Other infectious complications assessment like intra abdominal abscess, postoperative pancreatitis, cholangitis, urinary tract infection, pneumonia, sepsis and length of hospital stayTimepoint: TILL 3 MONTHS | — |
Countries
India
Contacts
Public ContactRAPOLU SRI CHANDANA DEEPTHI
POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH,CHANDIGARH
Outcome results
None listed