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How Probiotics Could Help the Heart Heal After a Heart Attack

Deciphering the Gut-Cardiovascular Nexus: Probiotic-Induced Modulation of Post-Myocardial Infarction Recovery Mechanisms - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092911
Enrollment
30
Registered
2025-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I219- Acute myocardial infarction, unspecified

Interventions

Intervention1: Adjuvant: Bioticas - 5 billion CFU per day, twice a day (BD), oral for 12 weeks Control Intervention1: Bioticas: Lactobacillus acidophillus, Lactobacillus rhamnosus, Bifidobacterium lon

Sponsors

Individual
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Both Inpatients & Outpatients above 18 and below 75 years. Patients who has been diagnosed with Myocardial Infarction. Patients who agrees to participate by knowing the nature and objectives of the study, and willing to take the Informed consent. Patients with elevated LDL cholesterol levels greater than 100 mg per dL and or increased hs-CRP levels greater than or equal to 3 mg per L. Patients with documented left ventricular dysfunction Ejection Fraction less than or equal to 50%

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Significant decrease in hs-CRP levels, indicating reduced systemic inflammation and lower cardiovascular risk. Reduction in LDL cholesterol levels, contributing to decreased atherosclerosis progression and better lipid metabolism regulation. Improvement in left ventricular ejection fraction (LVEF) and other echocardiographic markers, suggesting better myocardial recovery and function. Patients receiving probiotics may experience better clinical recovery, reduced risk of recurrent cardiac events, and improved treatment satisfaction.Timepoint: 6 months data collections

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr SP Santhosh Kumar

Vivekanandha Medical Care Hospital

spsk1982@gmail.com9629858262

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026