Health Condition 1: O244- Gestational diabetes mellitus
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Kasturba Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant women diagnosed with GDM according to IADPSG criteria.
Exclusion criteria
Exclusion criteria: Pre-existing diabetes mellitus (Type 1 or Type 2) Medical conditions (hypertension, renal disease, thyroid disorders, epilepsy) Chronic or Acute Infections Use of medications known to affect glucose metabolism, like Insulin, Anti-diabetic medications, and hypolipidemic medications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in body fat indices: Fat weight, Body fat Percentage, Fat Mass Index, Fat Free mass index, Carnitine Palmitoyl Transferase 1 activity, and inflammatory marker levels: Tumour Necrosis Factor alpha, Interleukin 6 between Insulin Resistant GDM and healthy pregnant controlsTimepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Predictive association of Fat Mass Index, Carnitine Palmitoyltransferase 1 activity, & inflammatory markers Tumor Necrosis Factor-alpha & Interleukin-6 with composite adverse pregnancy defined as the occurrence of any one or more of the following: macrosomia, caesarean delivery, neonatal hypoglycaemia, or Neonatal Intensive Care Unit admission.Timepoint: At the time of delivery of baby;To correlate Body Fat Indices Fat Weight, Body Fat Percentage, Fat Mass Index, Fat Free Mass Index, Carnitine Palmitoyltransferase 1 activity, & inflammatory markers Tumor Necrosis Factor alpha, Interleukin 6 with Homeostasis Model Assessment of Insulin Resistance scoresTimepoint: Baseline | — |
Countries
India
Contacts
Public ContactMelwin Maben
Kasturba Medical College Manipal
Outcome results
None listed