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Does Oral Calcium Supplementation Reduce the Need for Phototherapy in Newborns

Efficacy of prophylactic oral calcium supplementation in reducing the need for phototherapy in neonates 35 weeks or older: A pilot trial - NEOCALPRO

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092884
Enrollment
80
Registered
2025-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P599- Neonatal jaundice, unspecified

Interventions

Intervention1: Oral calcium phosphate: Neonates will receive oral calcium phosphate at a dose of 40-50 mg/kg/day of elemental calcium, administered in two divided doses daily, starting within six hour

Sponsors

Dr Bhabesh Kant Chowdhry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hemodynamically stable Inborn neonates with a gestational age of 35 weeks or more

Exclusion criteria

Exclusion criteria: 1. Neonates requiring NICU admission 2. Presence of cephalohematoma or subgaleal hematoma 3. Major congenital anomalies 4. Isoimmune haemolytic anemia (Direct coomb s test positive) 5. Parental refusal to provide consent

Design outcomes

Primary

MeasureTime frame
Proportion of neonates required phototherapy until dischargeTimepoint: Until the baby was discharged from the hospital (usually day 3 of life)

Secondary

MeasureTime frame
Duration of phototherapyTimepoint: If baby required phototherapy during the admission, then the duration of phototherapy will be calculated;Rate of rehospitalization for the treatment of neonatal jaundiceTimepoint: Babies readmitted following the discharge for the treatment of neonatal jaundice in the first week of life;Incidence of hypercalcemia between the groupsTimepoint: Serum calcium levels will be measured on day 3 life, concurrently with the universal congenital hypothyroidism screening

Countries

India

Contacts

Public ContactDr Arnab Ghorui

All India Institute of Medical Sciences, Patna

drbhabeshkc@aiimspatna.org7871592369

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026