Health Condition 1: L100- Pemphigus vulgaris Health Condition 2: L102- Pemphigus foliaceous Health Condition 3: L120- Bullous pemphigoid Health Condition 4: L123- Acquired epidermolysis bullosa Health Condition 5: L959- Vasculitis limited to the skin, unspecified
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Control Intervention2: Dermatopathologist diagnosing the Immunofluorescence image: Single arm study comparing the diagnosis of same Direct Immun
Sponsors
Dr Aishwarya Dhanuka
Eligibility
Inclusion criteria
Inclusion criteria: 1) All DIF images (obtained from slides from skin biopsy samples) from patients with clinically suspected AIBDs and Vasculitis that are received in DIF lab 2) All DIF Images in DIF lab with confirmed and labelled diagnosis (AIBDs and Vasculitis) 3)Slides diagnosed as negative (For training of AI)
Exclusion criteria
Exclusion criteria: 1)Poor quality images obtained from slides which were obtained from biopsies with insufficient dermis 2)Formalin stained samples
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To assess the utility of AI in diagnostic algorithm of DIF microscopy. 2) To compare human interpretation of DIF slides with that of AI diagnosis. Timepoint: 24 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare different AI algorithms for their accuracy in diagnosis of DIF slides Timepoint: 24 months; To establish potential advantages of AI in improving time required in diagnosing and accuracy of interpretation of diseases : a) Autoimmune bullous diseases b) VasculitisTimepoint: 24 months | — |
Countries
India
Contacts
Public ContactDr Raghavendra Rao
Kasturba Medical College, Manipal
Outcome results
None listed