Health Condition 1: J99- Respiratory disorders in diseasesclassified elsewhere
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All Invasively ventilated children intubated for any indication, more than six months and up to 18 years of age shall be enrolled for the study
Exclusion criteria
Exclusion criteria: 1. Children who are not intubated 2. Children who are already on High Frequency Oscillatory ventilation. 3. Children with open chest (following surgery) 4. Children with raised Intra cranial pressure 5. children with post cardiac arrest, neuromuscular disorder, congenital heart disease, mechanical ventilation of more than 1-week, uncontrolled terminal illness, 6. Previous barotrauma (pneumothorax, pneumomediastinum or subcutaneous emphysema) 7. When treating consultant refuses to participate (Due to unacceptable Vt, hemodynamic instability, radiological/ clinical evidence of lung hyperinflation)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the agreement between the Functional residual capacity (FRC) calculated by single step decruitment method with the FRC measured at Zero end expiratory pressure using nitrogen multiple breath wash-in wash-out technique. Timepoint: To study the agreement between the Functional residual capacity (FRC) calculated by single step decruitment method with the FRC measured at Zero end expiratory pressure using nitrogen multiple breath wash-in wash-out technique. | — |
Secondary
| Measure | Time frame |
|---|---|
| To calculate Recruitment to inflation ratio between PEEP 5 and ZEEP by using technique described by Lu chen et al To compare the compliance of the recruited lung by using two different methods ( Single step method and direct FRC and EELV measurement using NMBW technique) Timepoint: Single point assessment | — |
Countries
India
Contacts
Rainbow Childrens Hospital