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To compare volume of air remaining in lung at the end of expiration in ventilated patients measured by two different methods

To study the accuracy of the functional residual capacity (FRC) calculated by single step decruitment method by comparing with the FRC measured at zero end expiratory pressure : A prospective observational study - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/092805
Enrollment
20
Registered
2025-08-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J99- Respiratory disorders in diseasesclassified elsewhere

Interventions

Intervention1: Nil: Nil

Sponsors

Rainbow Childrens Medicare Ltd
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Invasively ventilated children intubated for any indication, more than six months and up to 18 years of age shall be enrolled for the study

Exclusion criteria

Exclusion criteria: 1. Children who are not intubated 2. Children who are already on High Frequency Oscillatory ventilation. 3. Children with open chest (following surgery) 4. Children with raised Intra cranial pressure 5. children with post cardiac arrest, neuromuscular disorder, congenital heart disease, mechanical ventilation of more than 1-week, uncontrolled terminal illness, 6. Previous barotrauma (pneumothorax, pneumomediastinum or subcutaneous emphysema) 7. When treating consultant refuses to participate (Due to unacceptable Vt, hemodynamic instability, radiological/ clinical evidence of lung hyperinflation)

Design outcomes

Primary

MeasureTime frame
To study the agreement between the Functional residual capacity (FRC) calculated by single step decruitment method with the FRC measured at Zero end expiratory pressure using nitrogen multiple breath wash-in wash-out technique. Timepoint: To study the agreement between the Functional residual capacity (FRC) calculated by single step decruitment method with the FRC measured at Zero end expiratory pressure using nitrogen multiple breath wash-in wash-out technique.

Secondary

MeasureTime frame
To calculate Recruitment to inflation ratio between PEEP 5 and ZEEP by using technique described by Lu chen et al To compare the compliance of the recruited lung by using two different methods ( Single step method and direct FRC and EELV measurement using NMBW technique) Timepoint: Single point assessment

Countries

India

Contacts

Public ContactDr Latha

Rainbow Childrens Hospital

drfarhan@rainbowhospitals.in9866007602

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026