Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: inj.Dexmedetomidine will be started as a loading dose of 1mcg /kg over15minutes followed by an infusion rate of 0.2 - 0.7 mcg/kg/hour to maintain a RASS score of -3 or
Sponsors
SRM medical college and research centre,
Eligibility
Inclusion criteria
Inclusion criteria: Age more than 18 years to less than 60 years ASA I ,II,III Mechanical ventilated patients for less than 24hours
Exclusion criteria
Exclusion criteria: Patient with decompensated cardiovascular,Neurological,Renal and Hepatic diseases. Allergy to any of the study drugs Patient on Ionotropes or Vasopressor support Pregnant patients. patient non consent. patient with chronic opioid dependence. Blood loss more than 1.5litres.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the level of sedation with Dexmedetomidine and Midazolam plus Fentanyl using the Richmond Agitation Sedation Score(RASS).Timepoint: the level of sedation with Dexmedetomidine and Midazolam plus Fentanyl using the Richmond Agitation Sedation Score(RASS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Behavioural pain scale assessment. Time taken for Extubation. Hemodynamic changesTimepoint: hourly for first four hours and every fifth hourly till 24 hours | — |
Countries
India
Contacts
Public ContactYuvaraj Ponnambalam
SRM medical college and research centre,
Outcome results
None listed