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Making Nerve Blocks Better: Comparing 10 Percentage Dextrose and Normal Saline as Diluents for Nerve Blocks Under Ultrasound Guidance

Pilot Study: Comparing the Duration of Action in Ultrasound-Guided Nerve Blocks with 10 Percentage Dextrose Versus Normal Saline Addition - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092791
Enrollment
14
Registered
2025-08-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A: Patients receive Nerve BLock with Injection Lignocaine with Adrenaline 2 Percentage (12ml) along with injection Bupivacaine 0.5 Percentage (15ml) with 10 Percentage Dextrose(10

Sponsors

Vinayaka Missions Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA physical status 1,2 and 3. 2) Patient undergoing orthopedic limb surgeries both upper limb and lower limb. 3) Patients undergoing surgical or orthopedic wound debridement. 4) Patients undergoing split skin graft over the extremities

Exclusion criteria

Exclusion criteria: 1) Absolute contraindications to the use of peripheral nerve blocks such as allergy to local anesthetics, inability to cooperate, patient refusal. 2) Active infection at the injection site. 3) Pre-existing neural deficits along the distribution of the block. 4) Patients with coagulopathies. 5) Patients on antithrombotic drugs.

Design outcomes

Primary

MeasureTime frame
To assess and compare the duration of action in ultrasound-guided nerve blocks when using 10% dextrose as an additive versus normal salineTimepoint: 3 mins, 6 mins, 9 mins, 12 mins, 15 mins, 18 mins, 20 mins

Secondary

MeasureTime frame
1) To evaluate the onset of the analgesic effect in ultrasound-guided nerve blocks with 10% dextrose compared to normal saline. 2) To analyze the safety profile of the nerve blocks with 10% dextrose versus normal saline, considering any adverse events or complications. Timepoint: 3 mins, 6 mins, 9 mins, 12 mins, 15 mins, 18 mins, 20 mins

Countries

India

Contacts

Public ContactDr Nithanthini B

Vinayaka Missions Medical College and Hospital

KarthikSarma.Akella@gmail.com9730069543

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026