Comparing Intracanal Medicaments like calcium hydroxide TAP and bioceramic for Pain Relief in Symptomatic Apical Periodontitis

Comparative evaluation of Calcium Hydroxide, Triple Antibiotic Paste and Bioceramic as intracanal medicament on endodontic interappointment pain in patients with symptomatic apical periodontitis A Randomised Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092756

Enrollment

Registered

2025-08-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: 1 Calcium Hydroxide intracanal medicament 2 Triple Antibiotic Paste intracanal medicament 3 Bioceramic intracanal medicament: 20% calcium hydroxide intracanal dressing paste Triple ant

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age of the patient 18 to 50 years will be included in the study 2. Both males and females 3. Systemically healthy patients (Category: ASA Class 1) 4. Single rooted tooth diagnosed with symptomatic apical periodontitis. 5. Teeth with necrotic pulp that gave a negative response to vitality testing.

Exclusion criteria

Exclusion criteria: 1. Non-restorable teeth 2. Presence of endo-perio lesion 3. Teeth associated with acute or chronic apical abscess 4. Teeth with chronic periodontitis 5. Teeth with open apex 6. Teeth with calcified canals 7. Teeth with severe dilaceration 8. Teeth with internal/external root resorption 9. Patient who were allergic to medication that were used in study 10. Patient who were taking medicine that could influence pain perception 11. Patient that had serious medical illness 12. Patient with systemic disorder 13. Patient with immunocompromised disease such as AIDS or HBV.

Design outcomes

Primary

Measure	Time frame
To evaluate Calcium hydroxide Triple Antibiotic Paste and Bioceramic as intracanal medicaments on endodontic interappointment pain in patients with symptomatic apical periodontitis Timepoint: 6hrs 48hrs 72 hrs	—

Secondary

Measure	Time frame
2. To compare Calcium hydroxide, Triple Antibiotic Paste and Bioceramic as intracanal medicaments on endodontic interappointment pain in patients with symptomatic apical periodontitis. 3. To analyse Calcium hydroxide, Triple Antibiotic Paste and Bioceramic as intracanal medicaments on endodontic interappointment pain in patients with symptomatic apical periodontitis. Timepoint: 6hrs 48hrs 72 hrs	—

Countries

India

Contacts

Public ContactPrathamesh Sawant

Ranjeet Deshmukh Dental College and research Center Nagpur

makade.chetana@gmail.com9372690962

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026