Study comparing the dental implant stability and bone healing in patients receiving dental implants treated with bone regenerative liquid vs those with untreated dental implants

Effect of Bone Bioactive Liquid on Osseointegration A Randomized Controlled Trial Assessing Implant Stability and Bone Turnover Markers - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092752

Enrollment

Registered

2025-08-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K063- Horizontal alveolar bone loss

Interventions

Intervention1: nil: nil Intervention2: Bone Bioactive Liquid [ BBL ]: Bioactive Liquid (BBL) is a promising biostimulatory agent that may accelerate bone healing by modulating bone metabolism and enha

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are willing to replace the missing teeth with implants in single or multiple edentulous sites with Adequate bone height of 10mm and bone width of 6mm No systemic illness

Exclusion criteria

Exclusion criteria: Uncontrolled diabetics mellitus History of bone metabolic disorders History of smoking more than 10 cigarettes per day Inadequate bone volume Presence of untreated periapical kesions , cysts and tumours pregnancy and lactating mothers

Design outcomes

Primary

Measure	Time frame
The study is expected to demonstrate that the application of Bone Bioactive Liquid (BBL) at the implant site enhances osseointegration by improving implant stability and bone turnover activity compared to conventional implant placement.Timepoint: Baseline , 1 month and 3 months post implantation	—

Secondary

Measure	Time frame
Implant Stability Quotient (ISQ) values measured using Resonance Frequency Analysis (RFA)Timepoint: Baseline , 1 month & 3 months	—

Countries

India

Contacts

Public ContactD R N Shanmuganathan

Sri Ramachandra Institute of Higher Educatiin and Research

d0323001@sriher.edu.in9353451968

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026