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Case- control

Role of Iron Homeostasis and Vitamin D in Preeclampsia: A case-control study on Biochemical, Haematological, and Placental morphometric changes - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/092751
Enrollment
216
Registered
2025-08-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Control Intervention1: Case- control: Role of Iron Homeostasis and Vitamin D in Preeclampsia.

Sponsors

SWETANKA PRASAD
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria: i. Pregnant women aged between 18-35 years. ii. Preeclamptic and eclamptic women

Exclusion criteria

Exclusion criteria: Exclusion Criteria: i. Pregnant women having Type II Diabetes mellitus, gestational diabetes mellitus ii. Pregnant women with a hypertension history iii. Pregnant women who are on antidepressive medication iv. Thyrotoxicosis v. Connective tissue disease-systemic lupus erythematosus vi. Multiple pregnancy vii. Pheochromocytoma viii. Pregnant women who are not willing to give consent. ix. Failed to follow up x. Pregnant women undergoing blood transfusion.

Design outcomes

Primary

MeasureTime frame
A comprehensive understanding of how iron and vitamin D are regulated in different pregnancy conditions, particularly preeclampsia and eclampsia. Understanding the metabolic changes and placental morphometry related to iron and vitamin D, providing better management strategies for maternal health. Identification of key metabolites or metabolic patterns that distinguish normotensive pregnancies, preeclampsia, and eclampsia and could reveal biomarkers associated with iron homeostasis, inflammation, or oxidative stress. Timepoint: First trimester, Second trimester, and Third trimester

Secondary

MeasureTime frame
Evidence-based recommendations to the policy makers.Timepoint: First trimester, Second trimester, and Third trimester

Countries

India

Contacts

Public ContactSWETANKA PRASAD

Manipal-Tata Medical College, Jamshedpur (A Constituent Unit of MAHE, Manipal)

swetanka.prasad@manipal.edu9572921357

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026