Health Condition 1: J342- Deviated nasal septum
Conditions
Interventions
Intervention1: Intranasal Dexmedetomidine
: Intranasal dexmedetomidine 2 mcg/kg administered using an insulin syringe 45 60 minutes prior to induction. The drug is instilled in 0.3 ml increments, half
Sponsors
Dr Abin Thomas
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 to 60 years, ASA physical status I or II, undergoing elective septoplasty under general anaesthesia at AIIMS Mangalagiri, willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: Patients aged less than 18 or more than 60 years of age, known allergy to study drugs, pregnant or lactating women, BMI more than 30 kg perm , septoplasty lasting more than 120 minutes, refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric Rating Scale (NRS) pain score at the 4th postoperative hourTimepoint: primary outcome NRS pain score will be assessed at the 4th postoperative hour. So, the time point for the primary outcome is the 4th hour after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Requirement of additional intraoperative analgesics Timepoint: Throughout intraoperative period ;Requirement of rescue analgesics in postoperative period Timepoint: Within 24 hours postoperatively;Incidence of drug-related adverse effectsTimepoint: From drug administration until 24 hours postoperatively ;Sedation score using Ramsay Sedation ScaleTimepoint: Preoperatively and at 1, 4, 12, and 24 hours postoperatively ;Intraoperative and postoperative hemodynamic parameters (heart rate, blood pressure, MAP, SpO2)Timepoint: Intraoperatively every 15 minutes and postoperatively at 1, 4, 12, and 24 hours | — |
Countries
India
Contacts
Public ContactDr Abin Thomas
Department of Anesthesiology,AIIMS Mangalagiri
Outcome results
None listed