Health Condition 1: H661- Chronic tubotympanic suppurative otitis media
Conditions
Interventions
Intervention1: Nebulisation: The procedure will be performed 15 minutes before the anticipated intubation
Group A 1mcg/kg nebulized dexmedetomidine with 5ml normal saline
Group B 2mcg/kg nebulized dex
Sponsors
S Nijalingappa medical college
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients of ages 20 to 60 years American Society of Anaesthesiologists grade I or II of both gender Patients undergoing elective surgery requiring GA
Exclusion criteria
Exclusion criteria: Patient with a history of sore throat or upper respiratory tract infection Hemodynamically unstable patients Emergency patients Patents with a history of allergy to dexmedetomidine 5. Patients with a history of cardiac, liver, or renal disorders. 6. Patient with a difficult airway where the anticipated duration of laryngoscopy exceeded 15 seconds
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate and compare two different doses Group-A (1mcg/kg) and Group-B (2mcg/kg) of nebulized dexmedetomidine to attenuate haemodynamic stress response to laryngoscopy and intubation at different time interval during intubationTimepoint: THE PRIMARY OBJECTIVE PARAMETERS WILL BE MEASURED AT VARIOUS TIME POINT ARE T0 baseline before the procedure of nebulization T1 after nebulization T2 before tracheal intubation T3 after tracheal intubation T4 5 minutes after tracheal intubation T5 at the closure of skin incision T6 immediately after tracheal extubation T7 5 minutes after tracheal extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To estimate and compare the hemodynamic parameters in group A and group B at extubation. 2. To assess and compare the cough response at extubation and the incidence rate of postoperative sore throat between group A and group B. Timepoint: 6hours | — |
Countries
India
Contacts
Public ContactDr Soundarya G R
S Nijalingappa Medical College
Outcome results
None listed