A study comparing two anesthesia methods (Thoracic Segmental Spinal Anesthesia and Erector Spinae Plane Block) for pain relief after breast cancer surgery (modified radical mastectomy)

Comparative study of Thoracic Segmental Spinal Anesthesia and Erector Spinae Plane Block for modified radical mastectomy: A randomized controlled clinical trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092730

Enrollment

Registered

2025-08-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Thoracic Segmental Spinal Anesthesia (TSSA): Patients receive TSSA at T4 T5 interspace with 1.5 ml of 0.2% isobaric ropivacaine plus 5 mcg dexmedetomidine. Control Intervention1: Erecto

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willing to participate with written informed consent. 2. ASA grade I and II. 3. Patients age more than 18 years. 4. Patients undergoing modified radical mastectomy.

Exclusion criteria

Exclusion criteria: 1. ASA grade more than II. 2. Thrombocytopenia or coagulopathy. 3. Local site infection. 4. Spinal or chest deformity. 5. Surgery duration expected to exceed 3 hours.

Design outcomes

Primary

Measure	Time frame
Comparison of postoperative pain scores (VAS) between Group TSSA and Group ESPB.Timepoint: after 30 minutes and 2 hours post extubation	—

Secondary

Measure	Time frame
Incidence of adverse events (hypotension, bradycardia, nausea, vomiting, block-related complications).Timepoint: at 12 hours post operatively & at 24 hours postoperatively	—

Countries

India

Contacts

Public ContactDr Bhavna Sriramka

Department of Anesthesiology, Modular OT 3 complex, first floor, institute of medical sciences and sum hospital, Siksha o Anusandhan, Khordha, Odisha, India, 751003 Institute of medical sciences and sum hospital, Siksha O anusandhan Khordha ORISSA 751003

bhavna.sriramka@gmail.com94060333609

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026