Health Condition 1: R652- Severe sepsis
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
ESIC Medical College and Hospital, Faridabad
Eligibility
Inclusion criteria
Inclusion criteria: 1.Newly diagnosed cases of sepsis and septic shock as per sepsis 3 definition 2.Age 18-60 years
Exclusion criteria
Exclusion criteria: 1.Use of inotropes and vasopressors 24hrs prior to ICU admission 2.Insufficient echocardiographic image quality 3.Patient or relatives declining participation 4.Prescence of acute myocardial infarction, myocarditis and cardiac arrythmia 5.Post -cardiopulmonary resuscitation 6.Previous history of congenital heart disease, valvular heart disease, cardiomyopathy, and chronic heart failure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To measure the LV global longitudinal strain (GLS) and RV strain using 2D speckle-tracking echocardiography and classify the degree of myocardial impairment in both sepsis and septic shock patients. 2.To assess left ventricular (LV) and right ventricular (RV) function in patients with sepsis and septic shock using conventional echocardiographic parameters within 24 hours of ICU admission and at the time of recovery. Timepoint: Within 24 hours , at 72 hours and at 7 days or at recovery | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the reversibility of cardiac dysfunction in septic shock patients by performing a follow-up echocardiography at recovery (defined as discontinuation of inotropes or vasopressors).Timepoint: Within 24 hours , at 72 hours and at 7 days or at recovery | — |
Countries
India
Contacts
Public ContactYashita Joshi
ESIC Medical College and Hospital, Faridabad
Outcome results
None listed