A clinical comparative bupivacaine with dexmedetomidine and ropivacaine with dexmedetomidine as an adjuvant in thoracic epidural in abdominal surgeries

A clinical comparative study of bupivacaine with dexmedetomidine and ropivacaine with dexmedetomidine as an adjuvant in thoracic epidural for patients undergoing abdominal surgeries for post operative pain management - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092651

Enrollment

Registered

2025-08-08

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Bupivacaine with Dexmedetomidine: Inj Bupivacaine 0.5% 20 ml with Inj Dexmedetomidine 1 mcg/kg via epidural route Control Intervention1: Bupivacaine with Dexmedetomidine: Inj Bupivacain

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status 1 & 2 patients

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA: 1. Age less than 25 years and more than 60 years. 2. Unwilling patients not giving consent for operation. 3. ASA physical status class III or more. 4. Patients having known hypersensitivity to amide local anaesthetics and Dexmedetomidine. 5. Patients displaying sign and symptoms of systemic infection. 6.Patients having local infection in thoracic spinal region. 7. Patients with pre-existing Diabetes Mellitus, Hypertension, Ischaemic Heart Disease, COPD or any other major systemic illness. 8. Pre-existing CNS disorder-Epilepsy and raised intracranial tension. 9. Pre-existing respiratory disorder-COPD, Asthma, Chronic Bronchitis. 10. Severe renal, hepatic, cardiological, haematological, metabolic disorder. 11. Cardiovascular malformation. 12. Bleeding diathesis or coagulopathy. 13. Spinal deformity. 14. Patients on anticoagulant or antiplatelet therapy.

Design outcomes

Primary

Measure	Time frame
Post operative analgesia with duration of analgesiaTimepoint: From the time of insertion of epidural and drug given till the time patient starts complaining pain	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Richa Agarwal

LLRM Medical College

pcllrm@gmail.com9557040620

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026