Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Intervention1: Topical Tofacitinib 2% Ointment + Topical corticosteroid (betamethasone dipropionate 0.05%): Topical tofacitinib 2% ointment applied once daily at night along with betamethasone dipropi
Sponsors
Government Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients with chronic plaque psoriasis not requiring systemic medication
Exclusion criteria
Exclusion criteria: Non-plaque forms of psoriasis History or evidence of psoriatic arthritis Use of any systemic agent or phototherapy in the last 2 weeks Any co-existing serious systemic illness requiring long-term medication Any infection requiring hospitalization within the past 2 weeks Pregnancy/lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage reduction in Psoriasis Area and Severity Index (PASI) scoreTimepoint: at 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of patients achieving PASI 50 & PASI 75 responsesTimepoint: At baseline & 12 weeks;Change in Physician s Global Assessment (PGA) scoreTimepoint: Baseline and 12 weeks;Change in patient satisfaction scoresTimepoint: Baseline and 12 weeks;Incidence of adverse effects and overall tolerabilityTimepoint: Baseline to 12 weeks | — |
Countries
India
Contacts
Public ContactDr Aarshia Bajaj
Government Medical College and Hospital, Sector 32, Chandigarh
Outcome results
None listed