Health Condition 1: J708- Respiratory conditions due to other specified external agents
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Intervention4: Nil: Nil
Sponsors
Maulana Azad Medical college
Eligibility
Inclusion criteria
Inclusion criteria: 1.Children between 1 month to 12 years requiring mechanical ventilation 2.Mechanical ventilation for more than 24 hours 3.Admission to Pediatric intensive care unit or Pediatric High dependency unit in department of Pediatrics, MAMC and associated LN Hospital
Exclusion criteria
Exclusion criteria: 1.Children with known diagnosis of Myasthenia Gravis, Guillian barre syndrome, Amyotropic lateral sclerosis, Cervical spinal cord injury, and Spinal muscular atrophy, bronchopleural fistula. 2.Children those who were ventilated for more than 24 hours prior to presentation into Intensive care unit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patient with Ventilator Induced diaphragmatic dysfunction in Mechanically ventilated patientTimepoint: 2 week | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Factors associated with causation of Ventilator induced diaphragm dysfunction including muscle wasting (as assessed by QFMT, skin fold thickness), inotrope requirement (as assessed by mean vasoactive inotropic score), oxygen requirement (as assessed by mean oxygenation index ), calorie intake, presence of AKI, delay in starting feeds, drug associated sarcopenia, dyselectrolytemia, ventilation parameters etc.Timepoint: 2 week;2. Association of Ventilator induced diaphragmatic dysfunction with clinical outcomes such as mortality, duration of stay, duration of ventilation etc.Timepoint: 2 week;3. Diaphragmatic thickness fraction ratio as a predictor of success of spontaneous breathing trial and extubation success.Timepoint: 2 week | — |
Countries
India
Contacts
Public ContactDrRomit Saxena
Maulana Azad Medical College
Outcome results
None listed