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To assess the effectiveness of of two local anesthetic agents, namely articane and lignociane, to provide anesthesia of the dental pulp of hypomineralized second primary molars requiring root canal treatment in 6-9 year old children.

Comparative evaluation of the anesthetic efficacy of 4% Articaine versus 2% Lignocaine in root canal therapy of hypomineralized second primary molars: A split-mouth, double-blinded, randomized controlled trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092581
Enrollment
20
Registered
2025-08-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: 4% articaine in 1:100,000 epinephrine: Maximum dose of 4% articaine will be calculated based on the weight of individual patient (maximum 7mg/kg). The anesthetic agent will be administe

Sponsors

Olando Kevin Dsouza
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Positive or absolute positive behavior according to Frankl behavior classification (Frankl et al. 1962) 2. Bilateral mandibular hypomineralized second primary molars (diagnostic criteria by Ghanim et al. 2017), with signs of irreversible pulpitis and requiring root canal therapy 3. Children who are not under the effects of analgesics or sedatives 4. Parents will be willing to provide a written informed consent to participate in the study

Exclusion criteria

Exclusion criteria: 1. Children with known allergy to the anesthetic agents used 2. Teeth with non-vital pulp

Design outcomes

Primary

MeasureTime frame
Anesthetic efficacy of 4% articaine versus 2% lignocaine, when administered as an inferior alveolar nerve block (IANB) for root canal therapy of hypomineralized mandibular second primary molarsTimepoint: 1. on injection 2. during access opening 3. during instrumentation—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactOlando Kevin Dsouza

Goa Dental College and Hospital

olandokevindsouza@gmail.com9284796376

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026