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Effect of neuromuscular blockade on post operative diaphragmatic function

Effect of shallow vs moderate neuromuscular blockade in major abdominal surgeries on post operative diaphragmatic function- a randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092546
Enrollment
136
Registered
2025-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C15-C26- Malignant neoplasms of digestive organs Health Condition 2: K20-K31- Diseases of esophagus, stomach and duodenum Health Condition 3: K50-K52- Noninfective enteritis and colitis Health Condition 4: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 5: K55-K64- Other diseases of intestines Health Condition 6: K35-K38- Diseases of appendix Health Condition 7: K42- Umbilical hernia Health Condition 8: K43- Ventral hernia Health Condition 9: N1

Interventions

Intervention1: Application of shallow neuromuscular blockade in major abdominal surgeries.: Pre operative diaphragmatic thickness fraction will be monitored Induction dose of Atracurium will be giv

Sponsors

All India Institute of Medical Sciences, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing major abdominal surgery with an expected duration of at least 2 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
To compare the effect of shallow vs moderate neuromuscular blockade on post operative diaphragmatic thickness fraction 60 minutes after extubation in patients undergoing major abdominal surgery with an expected duration of at least 2 hours.Timepoint: To compare the effect of shallow vs moderate neuromuscular blockade on post operative diaphragmatic thickness fraction 60 minutes after extubation in patients undergoing major abdominal surgery with an expected duration of at least 2 hours.

Secondary

MeasureTime frame
To assess the the effect of shallow vs moderate neuromuscular blockade on post operative lung ultrasound score & DETimepoint: 60 minutes after extubation;To assess the incidence of POPCTimepoint: POD 3;To assess patient centred outcomes like duration of ICU stay and hospital stayTimepoint: Post operative Hospital stay

Countries

India

Contacts

Public ContactArju Choudhary

AIIMS New Delhi

bhattacharjee.sulagna85@gmail.com9818212531

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026