Helping Cancer Patients Feel Better: Testing Stress Checks and Tailored Support During Radiotherapy.

A Randomised Single Blinded Trial Assessing the Impact of Routine Distress Screening and Personalised Interventions on Quality of Life and Distress in Cancer patients Undergoing Radiotherapy. - nil

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092544

Enrollment

200

Registered

2025-08-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-D49- Neoplasms

Interventions

Intervention1: NCCN Distress Thermometer and problem list: Arm A (Intervention group) Patients will undergo routine distress screening using the NCCN Distress Thermometer (DT) and Problem List prior t

Eligibility

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed cancer patients planned for definitive or upfront radiotherapy or chemoradiotherapy at Dr B Borooah Cancer Institute. 2. Performance Status: ECOG Performance Status of 0-2 3. Patients must be willing to provide informed consent for participation in the study.

Exclusion criteria

Exclusion criteria: Exclusion Criteria: o ECOG Performance Status greater than or equal to 3. o Age less than or equal to 18 years. o Diagnosis of depression or mood disorder, and patients on antidepressants and anti-psychotics from before o Patients who have previously undergone neoadjuvant chemotherapy, surgery, or radiotherapy. o Treated with palliative intent. o Patients who do not provide informed consent to participate in the study.

Design outcomes

Secondary

Measure	Time frame
Factors influencing distress among patients will be identified which will help us to develop prophylactic measures for these group of patients upfront.Timepoint: At the start of radiotherapy, weekly and at the end of radiotherapy.;Additionally, expecting to see improved quality of life scores in the screening group compared to the standard care group.Timepoint: QOL will be assessed at beginning and end of radiotherapy using a validated QOL tool EORTC QLQ-C30 in both the arms.	—

Measure

Time frame

Factors influencing distress among patients will be identified which will help us to develop prophylactic measures for these group of patients upfront.Timepoint: At the start of radiotherapy, weekly and at the end of radiotherapy.;Additionally, expecting to see improved quality of life scores in the screening group compared to the standard care group.Timepoint: QOL will be assessed at beginning and end of radiotherapy using a validated QOL tool EORTC QLQ-C30 in both the arms.

—

Primary

Measure	Time frame
Anticipating that routine distress screening and timely interventions will significantly reduce the psychological and practical challenges faced by cancer patients.Timepoint: At the start of radiotherapy, weekly and at the end of radiotherapy.	—

Countries

India

Contacts

Public ContactTapashi Das

Dr. B. Borooah Cancer Institute

dastapsee02@gmail.com6000718754

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026