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A study on intra and post operative bleeding Control after tooth removal in patients using blood thinners with Blue laser light, antifibrinolytic agent (Tranexamic Acid) and Chitosan dressing- An Invivo study.

Comparison of post-extraction bleeding control in patients on dual antiplatelet therapy: A randomized controlled trial evaluating the efficacy of 470nm Blue laser, Tranexamic Acid and Chitosan. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092524
Enrollment
44
Registered
2025-08-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: K045- Chronic apical periodontitis

Interventions

Intervention1: Chitosan: Immediately after Extraction, Placement of Chitosan Wound Dressing will be done & sutured, By Axiostat company, Haemostatic agents. Intervention2: 470nm Blue Laser: Wavelength

Sponsors

Dr Talari Divya Sri
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients aged 40-60 Years. 2.Patients on dual antiplatelet therapy 3.Patients requiring single molar tooth extraction 4.Patients willing to consent for the study.

Exclusion criteria

Exclusion criteria: 1.Patient with INR more than 2. 2.Patients with Periapical pathology, requiring Trans alveolar extraction, Patients with Uncontrollable Blood Pressure greater than 140/90 mm of Hg and Diabetes Mellitus, Liver disease, Alcoholics, Smokers and Patients on Anticoagulants or on Other Allied Medications, Hemostasis Achieved more than 20 Minutes.

Design outcomes

Primary

MeasureTime frame
Hemostasis confirmed using Filter paper method & to measure the time for Hemostasis in each of the interventional groups. Timepoint: Immediately after the extraction, for 8 minutes.

Secondary

MeasureTime frame
Total amount of blood loss using Gravimetric method Wound healing scale using Landrys healing index Post-operative complications Satisfaction 5 point Likert scale Post-operative Pain using VAS Need for any hemostatic interventions Timepoint: During treatment &follow up on postop day-7.

Countries

India

Contacts

Public ContactDr Anil B

Oral & Maxillofacial Surgery Department

anil@vdc.edu.in8142138848

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026