A study comparing normal tissue doses and toxicity profile in two different techniques for Craniospinal irradiation

Prospective Comparative study of Dosimetry and Hematological profile in Craniospinal Irradiation with Full versus Partial arc technique - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092483

Enrollment

Registered

2025-08-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C716- Malignant neoplasm of cerebellum

Interventions

Intervention1: Craniospinal irradiation by partial arc technique: One group will receive radiotherapy of craniospinal axis by partial arc therapy Control Intervention1: Craniospinal irradiation by ful

Eligibility

Inclusion criteria

Inclusion criteria: Biopsy proven Medulloblastoma patients. Age more than 3 years. Those who are willing to give written informed consent. KPS/Lansky more than equal to 70 years

Exclusion criteria

Exclusion criteria: 1. Those with widespread disease and not suitable for definitive intent treatment 2. Those who have received prior chemotherapy.

Design outcomes

Primary

Measure	Time frame
To compare organs at risk doses includng low dose spillage volume of individual radiotherapy plans.Timepoint: At baseline.	—

Secondary

Measure	Time frame
Hematological toxicity during and after radiotherapy treatment.Timepoint: During radiotherapy and 1 month after completion of treatment.	—

Countries

India

Contacts

Public ContactDr Renu Madan

Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh

renumadan10@yahoo.com9868597027

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026