Health Condition 1: K801- Calculus of gallbladder with othercholecystitis Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Propofol group: In the propofol group, anaesthesia will be maintained by administration of propofol using Schneider pharmacokinetic model of Target-Controlled In
Sponsors
Maulana Azad Medical College and associated Lok Nayak Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients having American Society of Anesthesiologists (ASA) physical status I and II. 2. BMI less than or equal to 30 kg/m
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating patients 2. History of allergy to any study drug 3. Patients on antipsychotics medications 4. Neurological disorders and ophthalmic disordersaffecting pupillary size or reaction 5. History of head trauma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pupillary diameter (PD) in patients undergoing propofol and sevoflurane anesthesia at the time of incision at comparable depths of sedation and nociception.Timepoint: TO (Baseline) - before induction T1 - 1 min after induction T2 - At skin incision T3 - During trochar insertion every 15 min interval following T3 At the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Pupillary diameter at other predefined time intervals Timepoint: TO (Baseline) - before induction T1 - 1 min after induction T2 - At skin incision T3 - During trochar insertion every 15 min interval following T3 At the end of surgery;Change in pupillary diameters from baseline diameters at various predefined time intervals during the procedureTimepoint: TO (Baseline) - before induction T1 - 1 min after induction T2 - At skin incision T3 - During trochar insertion every 15 min interval following T3 At the end of surgery | — |
Countries
India
Contacts
Public ContactDR Bharti Wadhwa
Maulana Azad Medical College and associated hospitals
Outcome results
None listed