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A First Look at How Lymphatic System Issues May Cause Persistent Fluid retention in the abdomen of the recipient After a Liver Transplant

Correlation between Persistent Post Liver Transplantation Ascites and Lymphatic Molecular Dysfunction: A Pilot study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/092444
Enrollment
50
Registered
2025-08-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K720- Acute and subacute hepatic failure Health Condition 2: K703- Alcoholic cirrhosis of liver Health Condition 3: K754- Autoimmune hepatitis Health Condition 4: K766- Portal hypertension Health Condition 5: K743- Primary biliary cirrhosis Health Condition 6: K744- Secondary biliary cirrhosis

Interventions

Intervention1: Nil: Nil

Sponsors

Institute of Liver and Biliary Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All prospective recipients who underwent LDLT in the Department of HPB Surgery and Liver Transplantation, Institute of Liver and Biliary Sciences.

Exclusion criteria

Exclusion criteria: Negative consent, Acute liver failure, DDLT

Design outcomes

Primary

MeasureTime frame
To assess the degree of lymphatic dysfunction and its correlation with persistent post liver transplant ascites.Timepoint: 4 weeks—

Secondary

MeasureTime frame
RNA isolation & RT-PCR analysis of specific genes (Identity markers- PDPN, LYVE1, CD31). To identify the perioperative risk factors & postoperative sequelae of lymphatic dysfunction.Timepoint: on the day of surgery, postoperative day 3, 7, 14—

Countries

India

Contacts

Public ContactVeluru Gautham

INSTITUTE OF LIVER AND BILIARY SCIENCES

viniyendra@gmail.com9440346072

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026