Comparison study- Is injecting insulin into the keloid as useful as injecting steroid

Efficacy and Safety of Intralesional Insulin in Comparison to Intralesional Corticosteroids in the Management of Keloids: A Non Inferiority Trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/08/092355

Enrollment

Registered

2025-08-04

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L918- Other hypertrophic disorders of the skin

Interventions

Intervention1: Insulin: Injecting Inj.Actrapid 10IU per mL into keloid at day 0, Week 3, Week 6, Week 9 Control Intervention1: Triamcinolone acetonide: Injecting Inj.Triamcinolone acetonide 40mg per m

Eligibility

Inclusion criteria

Inclusion criteria: No prior treatment for keloids in the past 2 months and are willing to follow up

Exclusion criteria

Exclusion criteria: Pregnancy, Lactation, patient on immunosuppressants and anticoagulants, local site infection, ear lobe keloid, hypertrophic scars, diabetes

Design outcomes

Primary

Measure	Time frame
Compare the effectiveness of keloid severity using Vancouver scar scaleTimepoint: Baseline, week 9 and week 24	—

Secondary

Measure	Time frame
1.To assess and compare individual components of VSS (vascularity, height, pliability and pigmentation) 2.Compare the adverse effect 3.Recurrence rateTimepoint: Baseline, week 9 and week 24	—

Countries

India

Contacts

Public ContactM Nisha

Indira Gandhi Medical College and Research Institute

saritha_mohanan@yahoo.co.in9443397873

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026