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Making breathing tube placement easier: comparing two medicines and their mix used as a mist to help patients stay calm and comfortable when awake

Effect of nebulization with lignocaine, dexmedetomidine and lignocaine with dexmedetomidine on degree of ease of fiber-optic intubation. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092336
Enrollment
60
Registered
2025-08-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 4% Lignocaine 5ml: Glycopyrrolate 0.2mg IM will be given 30 minutes before surgery and two drops of 0.1% Xylometazoline will be instilled in both the nostrils. Patients will be nebuli

Sponsors

Gandhi Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA Grade - I , II Age group 18-60 years of either sex All patients scheduled to undergo elective surgery in the supine position under general anaesthesia

Exclusion criteria

Exclusion criteria: Thrombocytopenia or coagulopathy Nasal polyp, nasal obstruction and h/o previous nasal surgeries Non-cooperative patients Pregnant females Patients allergic to study drug

Design outcomes

Primary

MeasureTime frame
To evaluate the ease and success rate of fibreoptic intubation after nebulisation using lignocaine with dexmedetomidine, lignocaine alone and dexmedetomidine alone.Timepoint: Study starts 30 minutes prior to fibreoptic intubation till 15 minutes post intubation

Secondary

MeasureTime frame
To observe the hemodynamic parameters in three groups.Timepoint: The hemodynamic parameters recorded are heart rate, O2 saturation, systolic & diastolic blood pressure. These parameters will be recorded at baseline, after nebulization for 20 minutes & at 1 minute, 3 minutes, 5 minutes & 15 minutes post intubation.

Countries

India

Contacts

Public ContactDr Neelesh Nema

Gandhi Medical College

1074vicky@gmail.com9229983164

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026