Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
Conditions
Interventions
Intervention1: gastric pH and gastric ultrasound: not available
Intervention2: gastric pH and gastric ultrasound: Vonoprazan 20mg or Pantoprazole 40mg will be administered orally night before the surg
Sponsors
Department of Anaesthesia and Intensive Care
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosed with Type 2 Diabetes Mellitus. ASA physical status one to three Scheduled for elective surgeries under general anaesthesia.
Exclusion criteria
Exclusion criteria: History of gastrointestinal surgery. Known acid-peptic disorders or gastric motility disorders. Use of acid-suppressive therapy within 72 hours prior to surgery. Pregnancy or lactation. Obesity (BMI more than 35 kg per metre square) Known renal or hepatic dysfunction. Allergy to study drugs Patients already on PPI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The pH of gastric content will be recorded using pH meter in both the groups.Timepoint: Patients will be transferred to the post-anaesthesia care unit (PACU), where they will be monitored for the incidence of postoperative nausea and vomiting (PONV) at 1 hour, 6 hours, and 24 hours postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the gastric residual volume in both the study groups. To evaluate any drug-related adverse events of Vonoprazan & Pantoprazole. To study the incidence of postoperative nausea & vomiting upto 24 hours in the post- operative period.Timepoint: Patients will be transferred to the post-anaesthesia care unit (PACU), where they will be monitored for the incidence of postoperative nausea & vomiting (PONV) at 1 hour, 6 hours, and 24 hours postoperatively. | — |
Countries
India
Contacts
Public ContactDr Richa Saroa
Government Medical College and Hospital 32 Chandigarh
Outcome results
None listed