Health Condition 1: A239- Brucellosis, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Maulana Azad Medical College and Lok Nayak Hospital
Eligibility
Inclusion criteria
Inclusion criteria: INCLUSION CRITERIA FOR GROUP 1: Children aged 1 to 12 years presenting with any of the following symptoms: 1. Fever lasting more than 7 days without a known cause. 2. Joint pain (intermittent or migratory pain in large or small joints, or both, with or without limitation of movement). 3. Acute meningoencephalitis (presents with altered sensorium for more than 24 hours and at least one of the following features: fever, seizures, or focal neurological deficit, with cerebrospinal fluid showing more than 5 cells, glucose less than 2/3 of normal, and protein more than 45 mg/dl). 4. Deep-seated abscess, such as liver abscess or splenic abscess (USG of the whole abdomen proven). 5. Fever with hepatomegaly, splenomegaly, or both. INCLUSION CRITERIA FOR GROUP 2: Children aged 1-12 years presenting with: Minor ailments.
Exclusion criteria
Exclusion criteria: EXCLUSION CRITERIA FOR GROUP 1: 1. Tested positive for any known cause. EXCLUSION CRITERIA FOR GROUP 2: None.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Prevalence of IgG and IgM anti-brucellosis antibodies among children aged 1 to 12 years presenting with fever +/- joint pain or acute meningoencephalitis or abdominal pain or deep-seated abscesses or hepatomegaly or splenomegaly or hepatosplenomegaly or cough or coryza for more than 7 days.Timepoint: Primary outcome: Prevalence of IgG and IgM anti-brucellosis antibodies among children aged 1 to 12 years presenting with fever or joint pain or acute meningoencephalitis or abdominal pain or deep-seated abscesses or hepatomegaly or splenomegaly or hepatosplenomegaly or cough or coryza for more than 7 days. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcome Proportion of children positive for IgM & IgG antibodies against brucellosis with or without brucella-like symptoms. Association with brucella with sociodemographic factors like contact with animals or exposure to excreta or urine of animals, & consumption of raw or unpasteurized milk & milk products. Timepoint: Secondary Outcome Proportion of children positive for IgM & IgG antibodies against brucellosis with or without brucella-like symptoms. Association with brucella with sociodemographic factors like contact with animals or exposure to excreta or urine of animals, & consumption of raw or unpasteurized milk & milk products. | — |
Countries
India
Contacts
Public ContactDr Anurag Agarwal
Maulana Azad Medical College
Outcome results
None listed