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How Flow of blood in the Wrist Changes After putting a Tube Through the Mouth into the lungs During Anesthesia: A Study Comparing People With and Without High Blood Pressure

A Prospective Observational Study to Compare the Sympathetic Vasomotor Response of the Radial Artery Using Resistive Index and Pulsatility Index Following Endotracheal Intubation in Hypertensive vs. Normotensive Patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/08/092284
Enrollment
80
Registered
2025-08-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil

Sponsors

Amala Institute of Medical Sciences, Thrissur, Kerala, India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Both Groups Age 18 65 years American Society of Anesthesiologists (ASA) physical status I III Scheduled for elective surgery under general anesthesia with endotracheal intubation 2. Hypertensive Group Diagnosed hypertension (SBP more than 140 mmHg or DBP more than 90 mmHg or on antihypertensive medication) 3. Normotensive Group No history of hypertension (SBP less than or equal to 140 mmHg and DBP less than or equal to 90 mmHg)

Exclusion criteria

Exclusion criteria: 1. Inability to provide informed consent 2. Patients with significant arrhythmias or other cardiovascular instabilities. 3. Patients with peripheral vascular disease affecting the upper limbs. 4. Patients on medications that could significantly alter vascular tone (like high-dose vasodilators and inotropes). 5. Pregnant patients. 6. Inability to obtain clear Doppler signals from the radial artery

Design outcomes

Primary

MeasureTime frame
1.To compare changes in RI and PI of the radial artery before and after endotracheal intubation between hypertensive and normotensive patientsTimepoint: at the end of 12 months—

Secondary

MeasureTime frame
1. To assess the correlation between blood pressure changes and Doppler ultrasound parameters. 2. To evaluate the time course of vascular response following intubation. 3. To determine if hypertensive patients exhibit greater vasomotor instability post-intubation compared to normotensive patients. Timepoint: at the end of 12 months—

Countries

India

Contacts

Public ContactDr Derlin Thomas

Amala Institute of Medical Sciences, Thrissur, Kerala, India

derlin.t@gmail.com9447768944

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026