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Can gentle bone stimulation help braces work faster?A look at one time vs two time treatment

Comparison of effectiveness of one time versus two time piezoperforation on the rate of orthodontic tooth movement:A three arm parallel study - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092283
Enrollment
57
Registered
2025-08-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K14- Diseases of oral cavity and salivary glands

Interventions

Intervention1: one time piezoperforation: three perforations with each perforation 1.5mm diameter,4mm depth,bilaterally at extraction space distal to canine with each perforation spaced 3mm apart veri

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Physically and mentally healthy individuals of both genders in the age group of 18-25 years 2.Class I malocclusion with bimaxillary protrusion 3.Class II division 1 malocclusion 4.Crowding 1-3mm assessed by little s index space requirement showing all four premolar extractions 5.No history of orthodontic treatment 6.Healthy teeth without any active lesions 7.Patients with full permanent dentition 8.Patients without any habit of alcohol intake and smoking

Exclusion criteria

Exclusion criteria: 1.Evidence of bone loss or periodontal problems 2.Patients with systemic diseases ,bleeding diathesis 3.Patients taking medication that can interfere with orthodontic tooth movement 4.Extractions other than 1st premolar extraction in the upper arch 5.Crowding greater than 3mm 6.Pregnant patients 7.Patients with removable appliances, additional appliances that could be unpredictable pain sources such as headgear and miniscrew 8.Patients who has undergone orthognathic surgery 9.Missing teeth except for third molars treatment with extractions (impacted or unerupted permanent teeth)

Design outcomes

Primary

MeasureTime frame
amount of tooth retractionTimepoint: The amount of tooth retraction will be measured at the 2nd(T1), 4th (T2), 8th (T3), and 12th (T4) weeks

Secondary

MeasureTime frame
Intensity of perceived pain measured on a 10cm visual analogue scaleTimepoint: t1-2 hrs after piezoperforation, t2-6 hrs , t3 12 hrs, t4 -24 hrs, t5 2 days

Countries

India

Contacts

Public ContactDr Mandava Prasad

Narayana Dental College and Hospital

drgowrisankar@gmail.com9440012443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026