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A study to see effects of remifentyl when given alone and when combined with dexmeditomidine on pain relieve and T-lymphocyte count in Ca breast patients undergoing Modified radical mastectomy

Comparison of remifentanyl and remifentanyl with dexmeditomidine on the analgesic effect in patients undergoing modified radical mastectomy and it s influence on peripheral T-lymphocyte count:A Double Blinded RCT - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092229
Enrollment
58
Registered
2025-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: Remifentyl with dexmeditomidine: Inj Remifentyl and injection dexmeditomidine intraopertively just 15min before induction till skin closure Control Intervention1: Remifentyl: Remifentyl

Sponsors

Rasmita Rout
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient planned for Modified mastectomy surgery,age-18-65yrs,ASA grade 2&3 ,patients, weight 45-75kg

Exclusion criteria

Exclusion criteria: Patients :with other malignant tumors, With other diseases of brain, kidney, heart,liver. With Stage 4 cancer With infectious disease history or drug addictions With cognitive dysfunction or other mental illness

Design outcomes

Primary

MeasureTime frame
Visual analogue scoreTimepoint: 4,8,12,16,20,24hrs after surgery—

Secondary

MeasureTime frame
Lymphocyte countTimepoint: Before and 24hrs after surgery;HemodynamicsTimepoint: Preop,intraop-after intubation,30min ,60,90min after intubation;Adverse effectsTimepoint: Within 48hrs after surgery—

Countries

India

Contacts

Public ContactRasmita rout

Department of anaesthesiology,AHPGIC, Cuttack

dr_sumita2007@yahoo.com9437022633

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026