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dental implant surface treatment by different chemicals before placement

Evaluation of Hard Tissue Outcomes Around Bisphosphonate - Coated and Injectable-Platelet Rich Fibrin - Coated Dental Implants: A Randomized Clinical Trial - nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/08/092222
Enrollment
42
Registered
2025-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: uncoated dental implants: uncoated implants will be placed as per standard procedure Control Intervention1: Bisphosphonate coating over dental implant: bisphosphonate coating will be ap

Sponsors

Institute of dental sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy adult patients requiring single or multiple dental implants Adequate interocclusal and mesiodistal space in the edentulous area Sufficient bone volume in the implant site confirmed through pre-operative CBCT

Exclusion criteria

Exclusion criteria: Patient with any systemic disease like uncontrolled diabetes hypothyroidism Patient with habits of smoking or heavy alcohol consumption parafunctional habit Patients currently undergoing steroids or medications which are known to affect bone metabolism osteoporosis and history or chemotherapy at least 6 months prior to implant placement coagulation defects or currently on anticoagulant treatment 4. Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
To assess and compare peri implant bone density and volume changes across bisphosphonate coated iPRF coated and uncoated implants using CBCT To evaluate extent of crestal bone level changes across three groups using CBCT Timepoint: 1 month 3 months 6 months post surgery

Secondary

MeasureTime frame
To evaluate extent of crestal bone level changes across three groups using CBCT Timepoint: 1 month 3 months 6 months post surgery

Countries

India

Contacts

Public ContactDr Akanksha Singh

Institute of dental sciences Bareilly

akkisingh014@gmail.com7081222230

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026