Health Condition 1: O048- (Induced) termination of pregnancywith other and unspecified complications
Conditions
Interventions
Intervention1: letrozole: T. Letrozole 10 mg OD for 3 days , followed by 800 mcg of misoprost pv after 72 hours.
Control Intervention1: T.MIFEPRISTONE 200 MG: T.Mifepristone 200 mg single dose followe
Sponsors
INHS ASVINI
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women more than 21 years of age with 2. Unwanted singleton pregnancies of upto 10 wks.
Exclusion criteria
Exclusion criteria: The exclusion criteria includes history or evidence of adrenal pathology, steroid-dependent cancer, porphyria, poorly controlled hypertension, bronchial asthma, thromboembolism and severe cardiac/renal/liver disease, Haemoglobin level less than 9.5 g/L, presence of an intrauterine contraceptive device, breastfeeding and reported allergic reaction to mifepristone, misoprostol or letrozole
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is achievement of complete abortionTimepoint: Time taken to achieve complete abortion 1week or 2 week | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes include time-to-abortion interval, the number of misoprostol doses required, healthcare resource utilisation and side effects.Timepoint: 2 yrs | — |
Countries
India
Contacts
Public ContactDR SHAZIA KHAN
INSTITUTE OF NAVAL MEDICINE
Outcome results
None listed