Health Condition 1: E440- Moderate protein-calorie malnutrition Health Condition 2: E43- Unspecified severe protein-caloriemalnutrition
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Cases Group 1: Children aged between 6 months-59 months with moderate acute malnutrition (weight for length/height Z-score between -3 to -2 and/or mid-upper-arm circumference between 11.5-12.5 cm) Group 2: Children aged between 6 months-59 months with moderate acute malnutrition (weight for length/height Z-score between less than -3Z and/or mid-upper-arm circumference between less than 11.5) Comparison Group: Children aged between 6 months-59 months with no undernutrition (weight for length/height Z-score between -1 to +1 and/or mid-upper-arm circumference more than 12.5 cms)
Exclusion criteria
Exclusion criteria: 1. Children with suspected or confirmed inborn error of metabolism or primary carnitine deficiency 2. Children on carnitine supplementation 3. Children with confirmed or suspected chronic kidney, chronic liver disease cardiomyopathy congenital heart disease and congenital malformation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum free carnitine levelsTimepoint: at Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. proportion of children with carnitine deficiency 2. proportion of children with carnitine insufficiency 3. correlate with lipid profile, total protein and serum albumin 4. correlate with age, gender, weight for height and mid upper arm circumferenceTimepoint: at Baseline | — |
Countries
India
Contacts
UCMS and GTB Hospital