Health Condition 1: G430- Migraine without aura
Conditions
Interventions
Intervention1: Yoga Module: Validated Yoga module including Asana, Pranayama, Kriya and Yoga Nidra.
Duration- 3 months,
Frequency- 5 days/week.
Control Intervention1: Control: No intervention provide
Sponsors
Shobhit Mishra
Eligibility
Inclusion criteria
Inclusion criteria: 21-45 years (Male and Female) Episodic Migraine (ICHD-3)- frequency 4-14 headache/month Diagnosis of migraine (with or without aura) for at least 6 months Willingness to participate in Yoga or control for 12 weeks. All medications except those known to influence/target CGRP levels potentially.
Exclusion criteria
Exclusion criteria: Other Neurological diseases Pregnant / Lactating Females /Planning pregnancy Alcohol disorder (AUDIT-C) Menstrual Migraine Recent neck or head injury Recent 6 months of yoga or any other alternative therapy Medication Overuse Headache (ICHD-3)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache Frequency (Self-Reported Through a Diary) Migraine Pill Count (Self-Reported Through a Diary) Visual Analogue Scale (VAS) Migraine-specific quality of life (MSQOL) Calcitonin Gene-Related Peptide (CGRP) Timepoint: Headache Frequency Baseline, week 1 to 12 (once in a week) Migraine Pill Count -Baseline, week 1 to 12 (once in a week) Visual Analogue Scale (VAS)- Baseline, week 1 to 12 (once in a week) Migraine-specific quality of life (MSQOL) Baseline and post (week 12) Calcitonin Gene-Related Peptide (CGRP) - Baseline and post (week 12) | — |
Secondary
| Measure | Time frame |
|---|---|
| Endothelial nitric oxide synthase (eNOS) hs-CRP (High-sensitive C-reactive Protein) RDW (Red cell distribution width) via CBC Migraine Interictal Burden Scale (MIBS-4) SATED (Sleep Health) Timepoint: Baseline & Post (week 12) | — |
Countries
India
Contacts
Public ContactShobhit Mishra
S-VYASA, deemed to be University
Outcome results
None listed