Study to assess the pain relieving effect of Meshasringi(Gymnema sylvestre) gel applied on the skin in patients with pain due to minor injury receiving treatment at Parul Institute of Ayurved, Vadodara

COMPREHENSIVE EVALUATION OF MESHASRINGI (GYMNEMA SYLVESTRE.(RETZ)R.BR.) GEL: ANALGESIC ACTIVITY IN ANIMAL TRIALS AND SINGLE GROUP PRETEST-POST TEST CLINICAL TRIAL TO ASSESS ANALGESIC EFFECTIVENESS IN PAINFUL TRAUMATIC INJURIES - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/092129

Enrollment

Registered

2025-07-31

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T148- Other injury of unspecified body region Health Condition 2: S809- Unspecified superficial injury ofknee and lower leg Health Condition 3: S999- Unspecified injury of ankle and foot Health Condition 4: S635- Other and unspecified sprain of wrist Health Condition 5: S934- Sprain of ankle Health Condition 6: S439- Sprain of unspecified parts of shoulder girdle Health Condition 7: S534- Sprain of elbow Health Condition 8: S300- Contusion of lower back and pelvis Health Cond

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult participants aged 18 to 75 years. 2.Confirmed diagnosis of painful traumatic injury. - Include participants with injuries classified as AIS 1 Minor and AIS 2 Moderate. 3.Ability to provide informed consent. 4.Individuals with Apparently steady vitals and health status 5.No known allergies or adverse reactions to any drug or topical medicines. 6.Adequate understanding of the study and willingness to comply with study procedures.

Exclusion criteria

Exclusion criteria: 1.Participants with injuries classified under AIS 3 (severe) and above AIS 4, AIS 5, AIS 6 2.Known case of HIV, VDRL, Hepatitis B, C or other infectious diseases 3.Subjects with contraindications for Meshasringi Gymnema sylvestre.(RETZ)R.BR. 4.History of allergies or adverse reactions to the components of Meshasringi Gymnema sylvestre.(RETZ)R.BR. Gel. 5.Serious comorbid medical conditions, skin disorders that could confound the assessment of analgesic efficacy in painful traumatic injuries. 6.Active bleeding disorders or use of anticoagulant therapy. 7.Pregnancy or lactation. 8.Inability or unwillingness to provide informed consent. 9.Unwillingness to comply with study procedures or attend follow-up visits.

Design outcomes

Primary

Measure	Time frame
1.Pain scores Visual Analog Scale Numeric Rating Scale 2.Inflammatory assessment changes redness warmth, swelling, tenderness 3.Range of movements Timepoint: 1.Pain scores Visual Analog Scale-Numeric Rating Scale assessed at base line, 30th minute, and 60th minute. 2.Inflammatory assessment changes such as redness warmth, swelling, tenderness will be assessed at base line and 60th minute of the application of the gels. 3.Range of movements will be assessed for the joints involved, and will be assessed at base line and 60th minute of the application using a goniometer	—

Measure

Time frame

1.Pain scores Visual Analog Scale Numeric Rating Scale 2.Inflammatory assessment changes redness warmth, swelling, tenderness 3.Range of movements Timepoint: 1.Pain scores Visual Analog Scale-Numeric Rating Scale assessed at base line, 30th minute, and 60th minute. 2.Inflammatory assessment changes such as redness warmth, swelling, tenderness will be assessed at base line and 60th minute of the application of the gels. 3.Range of movements will be assessed for the joints involved, and will be assessed at base line and 60th minute of the application using a goniometer

—

Secondary

Measure	Time frame
Duration of analgesia: Time period for which the analgesic effect is maintainedTimepoint: The duration of analgesic effect will be assessed by enquiring the patient regarding the same or the time will be recorded as when the patient informs when the pain score reaches the previous value	—

Countries

India

Contacts

Public ContactPRAVEEN P P

Parul University

dromprakashdave@gmail.com9460770626

Outcome results