Health Condition 1: J387- Other diseases of larynx
Conditions
Interventions
Intervention1: Intranasal dexmedetomidine: Intranasal dexmedetomidine at 1mcg/kg using atomizer 30 min before shifting to Operating room
Control Intervention1: Placebo: Intranasal normal saline using
Sponsors
AIIMS, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Age: 18 60 years ASA physical status I ,II and III Scheduled for elective suspension laryngoscopy for airway surgery under GA Patient giving written informed consent
Exclusion criteria
Exclusion criteria: Eye diseases (Diabetic Retinopathy, Glaucoma, Retinal Detachment etc.) History of elevated ICP (pseudotumor cerebri, hydrocephalus, Ventriculo-peritoneal shunt) Known allergy to Dexmedetomidine Severe cardiovascular or neurological disease Pregnancy Patient taking a methyldopa / clonidine/ other alpha 2 agonist
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Optic nerve sheath diameter (measured via ultrasound)Timepoint: T0- Pre-operative T1- Pre-intubation (Post induction of anaesthesia) T2- Just before removal of suspension laryngoscope T3- pre-extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| PRESSOR RESPONSETimepoint: Before induction (Baseline) Every minute post induction till suspension laryngoscopy removal ;Cough responseTimepoint: at extubation;Level of sedationTimepoint: Pre induction Post extubation 30 min | — |
Countries
India
Contacts
Public ContactDr Amit Kumar
AIIMS, New Delhi
Outcome results
None listed