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Comparison of efficacy and safety of Tazarotene 0.1% cream with Salicylic acid 12% ointment in fissured feet: A comparative prospective study

Efficacy and safety of Tazarotene 0.1% cream versus Salicylic acid 12% ointment in fissured feet: A randomized controlled study - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/092054
Enrollment
80
Registered
2025-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Tazarotene 0.1% cream: To be applied locally once daily at bedtime over affected area for total duration of 3 months, with follow ups once monthly Control Intervention1: Salicylic Acid

Sponsors

Kalinga Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients willing to give consent 2.Untreated fissuring of feet or xerosis

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating females 2.Non consenting participants 3.Immunocompromised patients 4.Skin disorders affecting the foot such as infections, dermatitis, psoriasis, un-healed skin wounds, ulcers or blisters. 5.Any participant with a known systematic disease including peripheral vascular disease or musculoskeletal disorders of the foot or ankle, rheumatoid arthritis will be excluded

Design outcomes

Primary

MeasureTime frame
Topical tazarotene 0.1% cream has equivalent efficacy in treatment of fissured feet in comparison to salicylic acid 12% ointmentTimepoint: Follow up will be done every month. Final assessment will be done after 3 months

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactPriyanshi Tyagi

Kalinga Institute of Medical Sciences

laxman.derm@gmail.com9500282040

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026