Skip to content

Study on injection and exercise for knee joint pain

Effectiveness of Intra-articular Injection with Strengthening Exercise versus Conventional Physiotherapy in Knee Osteoarthritis Patients - NIL

Status
Unknown
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/092001
Enrollment
60
Registered
2025-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: Intra-articular injection with strengthening exercise: 1st dose intra-articular injection, if pain abolish then no need further intra-articular injection. Pain still then 2nd dosages af

Sponsors

Dr Ehsanur Rahman Department of Physiotherapy and Rehabilitation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The inclusion criteria considered patients aged 40-70 years with knee osteoarthritis confirmed by a rheumatologist (grades I-III in the Kellgren-Lawrence score) who had pain, morning stiffness of shorter than 30 minutes, or knee crepitus.

Exclusion criteria

Exclusion criteria: Contraindication for IA injection such as overlying skin and soft tissue infection, uncontrolled bleeding diathesis, IA glucocorticoid injection in the past 3 months, patients with secondary OA due to inflammatory arthritis, trauma or infection or history of knee replacement in the same joint and planning for knee surgery within 3 months

Design outcomes

Primary

MeasureTime frame
Pain by Numeric Pain Rating ScaleTimepoint: 8 weeks intervention, a follow up will be conducted after 6 months

Secondary

MeasureTime frame
Physical function by Western Ontario and MacMaster Universities Osteoarthritis Index, Range of motion by Standard Goniometer, Lower limb muscle strength by 30 second Sit-to-Stand Test, Functional mobility by Timed Up and Go testTimepoint: 8 weeks intervention, a follow up will be conducted after 6 months

Countries

Bangladesh

Contacts

Public ContactDr Md Zahid Hossain

Jashore University of Science and Technology

mz.hossain@just.edu.bd8801670962775

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026