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Determination of the quality of life following nasal nerve surgery in patients of Allergic Rhinitis not responsive to medical treatment

Determination of the impact of Posterior Nasal Nerve Neurectomy in patients of Allergic Rhinitis intractable to medical management - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091991
Enrollment
90
Registered
2025-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J309- Allergic rhinitis, unspecified

Interventions

Intervention1: Patients undergoing Posterior Nasal Nerve Neurectomy with Inferior Turbinoplasty: Patients who meet the inclusion criteria undergoing posterior nasal nerve neurectomy with inferior turb

Sponsors

Dr Sneha Madhavarapu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. AGE – 18 to 50 years of age 2. Gender : Male and Female 3. Cases of Allergic Rhinitis: Patients with moderate/severe Persistent Allergic Rhinitis as per ARIA guidelines (symptoms for more than 4 days per week AND for more than 4 consecutive weeks per year; with one or more of the following : abnormal sleep, impairment of daily activities, sport, leisure, Problems caused at school or work, Troublesome symptoms) having 2 or more typical symptoms of Allergic Rhinitis - anterior or posterior rhinorrhoea, sneezing, nasal blockage and/or itching of the nose – who have shown no significant improvement in symptoms after Medical Management ( with Oral Antihistamines and Steroid Nasal Sprays for more than or equal to 1 month) 4. Allergic Skin Prick Test – Patient sensitized to 1 or more allergens. 5. Associated Anatomical variations such as Septal Deviation, Hypertrophied Turbinates. 6. Bronchial Asthma in addition to Allergic Rhinitis

Exclusion criteria

Exclusion criteria: 1. Congenital Anomalies of the nose 2. Patients post Sinonasal surgeries. 3. Sinonasal polyposis 4. Sinonasal malignancies 5. Previous radiation to Head and Neck 6. Head and neck trauma 7. Associated Syndromic conditions such as Kartagener’s syndrome, Young syndrome. 8. Bleeding Diathesis

Design outcomes

Primary

MeasureTime frame
Improvement in the quality of life of patients of Allergic Rhinitis intractable to medical management, post Posterior nasal nerve neurectomy by pre operative and post operative comparison of the SNOT 22 score and Total nasal symptom scoreTimepoint: 1 week, 1 month and 3 months post Posterior Nasal Nerve Neurectomy

Secondary

MeasureTime frame
1. Comparing the effectiveness of Posterior Nasal Neurectomy and Inferior Turbinoplasty and a combination of the two procedures (with or without septal correction) in reduction of symptoms of Allergic Rhinitis. 2. Assessment of the effect of Posterior Nasal Neurectomy on the specific symptoms of Allergic Rhinitis. Timepoint: 1 week, 1 month and 3 months post Posterior Nasal Nerve Neurectomy

Countries

India

Contacts

Public ContactSneha Madhavarapu

Kasturba Medical College, MAHE, Manipal

kailesh.pujary@manipal.edu9845144015

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026