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a study comparing two modes of ventilation in patients undergoing keyhole surgery.

Comparing two modes of ventilation in laproscopic surgeries in Trendelenburg position, Pressure Controlled Ventilation - Volume Guaranteed mode vs Volume Controlled Ventilation mode, A randomised controlled trial. - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091987
Enrollment
70
Registered
2025-07-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K35-K38- Diseases of appendix Health Condition 2: K80-K87- Disorders of gallbladder, biliary tract and pancreas Health Condition 3: N80-N98- Noninflammatory disorders of female genital tract

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Adithya Sony Raj
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective laparoscopic surgeries in Trendelenburg position. 2. ASA physical status I & II 3. BMI less than or equal to 30 Kg/m2

Exclusion criteria

Exclusion criteria: 1. Refusal for the study 2. Any contraindication for general anaesthesia 3. Severe obstructive or restrictive pulmonary disease 4. Suspected difficult intubation 5. Presence of any intracranial pathology

Design outcomes

Primary

MeasureTime frame
Peak airway pressure (P peak) after initiation of pneumoperitoneum measured at defined intervals.Timepoint: T1- 5 minutes after induction in the supine position and before initiation of the pneumoperitoneum. T2- 10 minutes after creation of pneumoperitoneum and achieving a stable peak pneumoperitoneum level of 12 14 mmHg for 5 minutes. T3- 15 minutes after positioning the patient in Trendelenburg position. T4- 10 minutes after pneumoperitoneum withdrawal, in the supine position.—

Secondary

MeasureTime frame
Respiratory mechanics like P mean & dynamic compliance in both the groupsTimepoint: intraoperative;Hemodynamic changes (SBP, DBP, MAP & HR) at defined intervals.Timepoint: intraoperative;Final ventilator settings - Expiratory tidal volume & respiratory rate required to achieve a stable ETCO2 of 35 - 40 mm of Hg.Timepoint: intraoperative;Incidence of sore throat in both groups & it will be assessed by a four-point categorical pain scale.Timepoint: intraoperative;ET tube insertion - number of attempts & success rate of insertion in both the groupsTimepoint: intraoperative;Oropharyngeal leak pressure (OLP)measured by closing the expiratory valve of closed circuit at fixed gas flow & noting the equilibrium airway pressure.Timepoint: intraoperative—

Countries

India

Contacts

Public ContactDr Jyothsna M

Ballari medical college and research centre, Ballari

jyothsnabk@yahoo.com9900055996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026