To study safety and efficacy of biomaterials in helping recovery of participants after spinal cord injury who are not able to walk

Safety and efficacy of biological scaffolds in patients with spinal cord injury - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/07/091977

Enrollment

Registered

2025-07-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G952- Other and unspecified cord compression

Interventions

Intervention1: biodegradable scaffold, exosomes, autologous bone marrow concentrate: Biodegradable scaffold implanted at the injury site, Exosomes isolated from human adipose mesenchymal stem cells (1

Eligibility

Inclusion criteria

Inclusion criteria: Acute spinal cord injury within 1 week having ASIA score A morbidity

Exclusion criteria

Exclusion criteria: Previous spinal surgeries, associated multisystem injuries, inability to comply with follow-up, no associated comorbidities

Design outcomes

Primary

Measure	Time frame
Improvement in the American Spinal Injury Association (ASIA) score, Functional independence measure (FIM) scoresTimepoint: 3, 6, 12 months and then yearly for 2 years.	—

Secondary

Measure	Time frame
Quality of life assessed by the EQ-5D scale, SCIM spinal cord independence measure, functional (10MWT, 6MWT, TUG, WISCI2)Timepoint: 1 month, 3 months, 6 months, 12 months, 2 years	—

Countries

India

Contacts

Public ContactProf Chooramani Gopal

Indian Institute of Technology Kanpur

ashokkum@iitk.ac.in9936491834

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026