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A Comparative study of effectiveness of two different drugs (alprazolam and melatonin) on the quality of sleep in patients posted for elective surgery

A Comparative study of effects of melatonin and alprazolam on the quality of sleep in patients posted for elective surgery - prospective randomised control study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091965
Enrollment
160
Registered
2025-07-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Medication: Medication will be given once at night per orally on the previous day of surgery Control Intervention1: Tablet Alprazolam 0.25 mg: Patients in group A will receive Tablet Al

Sponsors

Dr Janet Jassica J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) physical status Classes 1 and 2, posted for various elective surgeries.

Exclusion criteria

Exclusion criteria: Patients with OSA Patients with h/o insomnia and on insomnia medication Pregnant women Patients with any mental illness Patients on steroids and antipsychotics Trauma patients

Design outcomes

Primary

MeasureTime frame
a) sleep onset b) sleep duration c) sleep quality Timepoint: a) baseline before giving medication on the night before surgery and on the morning prior to surgery. b) baseline before giving medication on the night before surgery and on the morning prior to surgery. c) baseline before giving medication on the night before surgery and on the morning prior to surgery.

Secondary

MeasureTime frame
pre operative anxietyTimepoint: baseline before giving medication on the night before surgery & on the morning prior to surgery.

Countries

India

Contacts

Public ContactDr Vikram Shivappagoudar M

St. Johns Medical College and Hospital

msvikram681@gmail.com9731981665

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026