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Effect of Heartfulness Meditation on Mitochondrial Function

Effect of Heartfulness Meditation Practice on Mitochondrial Function: A Biochemical and Genomic Approach - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/07/091935
Enrollment
105
Registered
2025-07-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

Dr. Mansee Thakur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: participants will be from the age group 25-40 years, healthy (with no history of bacterial/viral/fungal infections in the past two months, no co-morbidities like diabetes, hypertension, PCOS/PCOD, etc.).

Exclusion criteria

Exclusion criteria: Dropout meditators unwilling to continue the practice or unable to do daily practice, attend group meditation session and individual session from 3 to 4 weeks Individuals with chronic conditions affecting mitochondrial function (e.g., diabetes, Hypertension, neurodegenerative diseases and cvd). Participants performing other yoga and meditation like brahma kumari, mindfulness, kriya yoga, Sahaj Yog etc. Inability to read or comprehend the consent form; subjects with medical conditions in which a blood draw would be contraindicated (e.g., severe anaemia); use of antibiotics or probiotic/prebiotic participants living outside of the country.

Design outcomes

Primary

MeasureTime frame
1. Mean Loneliness Score, 2. Mean Gratitude Score, 3. Mean Self-Consciousness Score, 4. Mean Comprehensive Intellectual Humility Score 5. Mean Well-being Score 6. Mean Burnout Score 7. Nicotinamide adenine dinucleotide (NAD/NAD+) and Cytochrome c Oxidase levels 8. Mitochondrial DNA copy number 9. Gene expression of key mitochondrial markers. 10. Mitochondrial membrane potentialTimepoint: This cross-sectional observational study involves the collection of blood samples from participants at a single point in time ie. Baseline. Blood samples will be analyzed to assess specific biomarkers relevant to the study objectives.

Secondary

MeasureTime frame
Meditation, particularly practices like Heartfulness, has been associated with enhanced mitochondrial function, offering insights into its cellular benefits. Studies show increased ATP production in meditators, indicating more efficient energy synthesis. Additionally, reduced oxidative stress and upregulated mitochondrial gene expression suggest improved cellular resilience and regulation. These biological changes reflect better mitochondrial health, serving as a potential mechanism underlying the broad health benefits of meditation. The findings deepen our understanding of how mind-body practices impact cellular function and open avenues for integrating meditation into therapeutic strategies to promote overall well-being by targeting mitochondrial efficiency and cellular homeostasisTimepoint: After one year

Countries

India

Contacts

Public ContactMs Amita Kirar

MGM School of Biomedical Sciences, MGMIHS

mansibiotech79@gmail.com9769909212

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026