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Comparing Two Common Medicines for Fever in Children: A Study of Paracetamol with high dose and Ibuprofen with regular dose

A randomised controlled trial comparing high-dose paracetamol and oral ibuprofen for fever management in children - NIL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091929
Enrollment
69
Registered
2025-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B999- Unspecified infectious disease

Interventions

Intervention1: PARACETAMOL: IF FEVER, AFTER RECORDING TEMPERATURE , HIGH DOSE PARACETAMOL (20MG/KG/DOSE) IS GIVEN ORALLY. THE DOSE WILL BE REPEATED AFTER 6 HOURS IF FEVER. DURATION OF TREATMENT TILL T

Sponsors

DR KANCHANKUMAR BHAGYAWANT
Lead Sponsor
DR JEEBAN KUMAR JENA
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients with fever (axillary temperature of more than 100 F) admitted to pediatric ward in Ruby Hall Clinic and willing to participate in study.

Exclusion criteria

Exclusion criteria: 1.Those patients who have received either of the drug in previous 6 hours. 2.Received antibiotics prior to admission. 3.Those receiving anti-coagulants warfarin, heparin etc. 4.Those patients having localized inflammatory pain. 5.Known case of asthma. 6.Known case of allergy to either drug. 7.Chronic cardiac or hepatic or renal failure requiring ICU care. 8.Any clinical adverse event or serious illness. 9.Those patients not willing to participate in study.

Design outcomes

Primary

MeasureTime frame
1. time taken to reduce fever by either of the drug 2. The decrease in fever associated discomfort following administration of either drug.Timepoint: AT BASELINE, 4 DAYS AND 8 DAYS

Secondary

MeasureTime frame
To determine any immediate adverse effects following drug administration.Timepoint: 24 hours

Countries

India

Contacts

Public ContactDR KANCHANKUMAR BHAGYAWANT

RUBY HALL CLINIC

mail2jeeban@gmail.com8763180697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026