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The Effect of Desflurane Switch at the End of Sevoflurane Based General Anaesthesia on Patient Emergence and Recovery

The Impact of Desflurane Switch at the Conclusion of Sevoflurane Based General Anaesthesia on Patient Emergence and Recovery: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/07/091912
Enrollment
90
Registered
2025-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Desflurane: General anaesthesia lasting more than 2 hours with sevoflurane switched to desflurane in last 30mins Control Intervention1: Sevoflurane: General anaesthesia lasting more tha

Sponsors

Dr Maria Clifson
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists 1 and 2 patients undergoing elective surgeries lasting more than 2 hours under general anesthesia

Exclusion criteria

Exclusion criteria: Patient refusal, Allergy to study drugs, Parturient, BMI more than 30, History or family history of malignant hyperthermia

Design outcomes

Primary

MeasureTime frame
To compare the eye opening time (the time when inhalational anaesthetic is stopped at the end of surgery till the patients first opened their eyes on verbal instruction) between sevoflurane and sevoflurane switched to desfluraneTimepoint: 18 months—

Secondary

MeasureTime frame
To compare the time to reach Bispectral Index 80 after discontinuing the inhalational anaesthetic between sevoflurane and sevoflurane switched to desfluraneTimepoint: 18 months;To compare the time to endotracheal extubation (the time between stopping administration of inhalational anaesthetic to endotracheal tube removal after sufficient recovery) between sevoflurane and sevoflurane switched to desfluraneTimepoint: 18 months—

Countries

India

Contacts

Public ContactDr Maria Clifson

MOSC Medical College Hospital, Kolenchery

drsam_p@hotmail.com9447209010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026